Colours from Publications

Patrick Cramer Lab

Three-step mechanism of promoter escape by RNA polymerase II:

Structure of paused transcription complex Pol II–DSIF–NELF：

Resolution of transcription-induced hexasomenucleosome complexes by Chd1 and FACT:

Promoter-proximal RNA polymerase II termination regulates transcription during human cell type transition:

Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair:

Structure of activated transcription complex Pol II–DSIF–PAF–SPT6:

Structural basis of nucleosome retention during transcription elongation:

Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription:

Structural basis for ATP-dependent chromatin remodelling by the INO80 complex:

In-cell architecture of the mitochondrial respiratory chain:

In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains:

Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-F0 coupling:

Structure of human PINK1 at a mitochondrial TOM-VDAC array:

Activation mechanism of PINK1:

Mechanism of parkin activation by PINK1:

The molecular structure of IFT-A and IFT-B in anterograde intraflagellar transport trains:

Structure of the dynein-2 complex and its assembly with intraflagellar transport trains:

mRNA recognition and packaging by the human transcription–export complex: